These images illustrate the general process of synaptic transmission. The
six steps in synaptic transmission are illustrated and described below.
Review these figures then take a look at the synaptic
transmission animation (48 k).
Step 1. The neurotransmitter is manufactured by the neuron and stored in
vesicles at the axon terminal.
Step 2. When the action potential reaches the axon terminal, it causes
the vesicles to release the neurotransmitter molecules into the synaptic
cleft.
Step 3. The neurotransmitter diffuses across the cleft and binds to
receptors on the post-synaptic cell.
Step 4. The activated receptors cause changes in the activity of the
post-synaptic neuron.
Step 5. The neurotransmitter molecules are released from the receptors
and diffuse back into the synaptic cleft.
Step 6. The Neurotransmitter is re-absorbed by the post synaptic neuron.
This process is known as Reuptake.
copyright (c) 2008 Michael R. Markham Updated:
April 25, 2008